Hoog boven de door oorlog verscheurde aarde, bemant Jack Harper de defensieve drones als hij verrast wordt door een beschadigd ruimtevaartschip.

In a world where families are limited to one child due to overpopulation, a set of identical septuplets must avoid being put to a long sleep by the government and dangerous infighting while investigating the disappearance of one of their own.

Set in the near future, Lockout follows a falsely convicted ex-government agent , whose one chance at obtaining freedom lies in the dangerous mission of rescuing the President's daughter from rioting convicts at an outer space maximum security prison.

Using footage left over from Nemesis 2 and a very thin story line sees Alex again fighting the cyborg mercenaries in 1998 East Africa. This time, Alex finds that she has 20 half sisters who are waiting for her to return to 2077. Central Command wants Alex captured alive and scanned to see if her DNA is a strong and more powerful strain than the normal. But Alex may be too tough for Farnsworth to capture.

It is the year 2077 and terrorist organization known as The Red Army Hammerheads now dominate the Earth. The fate of humanity now rests in the hands of The New Model, Ari Frost. Trained under the wing of Alex Rain, she must form an army of Cyborg Humans to take down the regime and regain control. After all, 86.5% is still considered human.