Although there are still traces of the brief period he became a vampire, third-year high school student Koyomi Araragi is human again. He happens upon others with their own supernatural problems and finds that he can empathize. Koyomi becomes involved in their lives, seeking to help them and occasionally asking for advice from Meme Oshino, the homeless man who helped him become human again.

When fate brings a half-human, half-vampire man and a cold-hearted woman together, they have to learn to care for each other.

Staz is a vampire from the surreal "Demon World", and Fuyumi, an ordinary girl, accidentally wanders into the Demon World through a portal. Subsequently after meeting each other, Fuyumi is killed by a carnivorous plant and turned into a ghost, causing Staz to take responsibility and pledge to help bring her back to life.

Paranormal photographer Kouhei stumbles into the arms of Hazuki, a vampire beauty who has waited for years to be freed from a forgotten castle. Unwilling to part with her unwitting hero, the petite vamp follows Kouhei home and starts causing trouble. But domestic disorder is the least of Kouhei’s problems. With dark forces gathering, he’s about to enter a world he can’t begin to comprehend!

Though enigmatic loner Pun has lived an exceedingly long life, he hasn't aged past about twenty-five. Yeah, Pun isn't some ordinary human. He has the blood of what some may call a vampire. Pun lives alone, modestly—like any regular person. One day, he meets a student named Yo. Yo becomes the first person Pun trusts and accepts into his life, and, without either realising it, that thing called love begins to develop between human and vampire.

Jun Ho is a vampire who is about to die. To survive, he will need to drink pure blood and thus become a human. One day, while searching for this pureblood, he meets Min Hyun, a human with pure blood. But another vampire named Hae Soo, who knows about Jun Ho's past traumas, causes Min Hyun and Jun Ho to fall out.