Three of the original five "young guns" — Billy the Kid, Jose Chavez y Chavez, and Doc Scurlock — return in Young Guns, Part 2, which is the story of Billy the Kid and his race to safety in Old Mexico while being trailed by a group of government agents led by Pat Garrett.

A legendary Native American-hating Army captain nearing retirement in 1892 is given one last assignment: to escort a Cheyenne chief and his family through dangerous territory back to his Montana reservation.

A group of young gunmen, led by Billy the Kid, become deputies to avenge the murder of the rancher who became their benefactor. But when Billy takes their authority too far, they become the hunted.

Will Lockhart arrives in Coronado, an isolated town in New Mexico, in search of someone who sells rifles to the Apache tribe, finding himself unwillingly drawn into the convoluted life of a local ranching family whose members seem to have a lot to hide.

New Mexico Territory, 1880. Rio Cutler and his older sister Sara must abandon their home after an unfortunate event happens. In their desperate flee to Santa Fe, they cross paths with the infamous outlaw Billy the Kid and his gang, who are ruthlessly pursued by a posse led by Sheriff Pat Garret.

New Mexico Territory, August 1879. The few surviving members of a cavalry column, which has been relentlessly decimated by the Apaches, attempt to reach Fort Crain. On their way through a hostile land, the obsessive and ruthless Sergeant Vinson takes to the limit the battered will of the troopers under his command.

A former gunslinger comes to the aid of ranchers battling a murderous land baron.