Frustrated with the direction of the church, Cardinal Bergoglio requests permission to retire in 2012 from Pope Benedict. Instead, facing scandal and self-doubt, the introspective Pope Benedict summons his harshest critic and future successor to Rome to reveal a secret that would shake the foundations of the Catholic Church.

In 1458, five years after the fall of Constantinople to the Turk, eighteen cardinals meet to elect a new pope. Rodrigo Borgia, a 27 year old cardinal learns to play a very dangerous game.