På en fjern ø opdager en gruppe forskere en 20 meter høj abe. De bringer vidunderet med tilbage til New York for at vise det frem. Desværre har de undervurderet monstrets styrke, og aben slipper løs for at drage hærgende igennem byens gader.

For the last decade, a team of frontline medics has been fighting to save Borneo's critically endangered orangutans. Armed with cameras, International Animal Rescue has documented their struggle: pulling apes from devastated jungle, giving emergency medical care, rehabilitating and releasing the healthiest orangutans back into the wild. This is both the story of their life-saving work and of how one of our closest wild relatives has been pushed to the brink of extinction. Combining genuine rescue footage with contributions from experts throughout, this documentary looks toward the future and asks what hope remains to save the orangutan.