Two children run away from a Swiss boarding school and set out for Paris, with their frantic parents in hot pursuit.

A precocious young girl and her younger brother run away from home and hide in the Metropolitan Museum in New York.

Three runaway girls hijack a car.

Heartless parents C.L. Doyle and his wife take two of their older children, Rosebud & Joseph T. Doyle, on a family vacation to Alaska, but dump their younger ones, Freddy & Margaret Jean, in a Los Angeles foster home. Infuriated by this, Rosebud talks Joseph T. into running away with her so that they can break their younger siblings out of the system, which sparks a manhunt, and an outburst of sympathy among kids everywhere.

15-year-old Andrea lives in a world of his own, where an innocent friendship with a pretty girl becomes a full-blown romance. He invites her to a motor show in nearby Bologna, but she fails to show up at the bus station. Instead, Andrea is joined by his older sister Stefania–who's planning a runaway with her boyfriend Angelo.

The film follows a simple structure, and shows the drug-related degradation of five youths (Jake, Tracey, Jessica, Alice, Oreo) during the course of three years. The film depicts drug-related crimes and diseases: prostitution, male prostitution, AIDS, and lethal overdoses.