Drones begins in the Nevada desert, where new girl Sue Lawson joins airman Jack in a hot, windowless bunker from which they manoeuvre unmanned drones across the plains of Afghanistan. Their first day at work is awkward but polite, with Jack all too aware of Sue’s privileged status as daughter of a well-respected general. This, however, will be no ordinary mission: as they train their sights on an unarmed terrorist suspect, a power struggle erupts between the smart, sophisticated Sue and the dogged, blue-collar Jack.

Little Henery the Chicken Hawk wants to prove he's big enough to hunt chickens, but he doesn't know what a chicken is. He labels Foghorn Leghorn a loud-mouthed shnook and dismisses him, prompting Foggy to indignantly try to prove he's a chicken and therefore fit to be Henery's prey.