In 1925, a group of brave mushers travel 700 miles to save the small children of Nome, Alaska from a deadly epidemic.

A beautiful but vain woman who rejects the love of her older husband must face the loss of her youth and beauty.

True story of the doctor who considered it was not immoral to search for a drug that would cure syphillis.

Cowboy Ross McEwen arrives in town. He asks the banker for a loan of $2000. When the banker asks about securing a loan that large, McEwen shows him his six-gun collateral. The banker hands over the money in exchange for an I.O.U., signed "Jefferson Davis". McEwen rides out of town and catches a train, but not before being bitten by a rattler. On the train, a nurse, Miss Hollister, tends to his wound. A posse searches the train, but McEwen manages to escape notice. However a mysterious Mexican has taken note of the cowboy, and that loudmouthed brat is still nosing around. Who will be the first to claim the reward for the robber's capture?

A doctor trying to fight a diphtheria epidemic comes into conflict with a police captain who is using all his resources to track down a cop-killer.

The daughter of a lighthouse keeper falls ill with diphtheria, but there is no doctor on the island. A wireless operator has the idea of contacting a passing passenger liner, to try and find a doctor.