16 gear, 18 hjul og tusindvis af hestekræfter. Rubber Duck kører lastbil, og han og kollegerne tager ikke Arizonas hastighedsgrænser alt for alvorligt. Snart er sherif "Dirty" Lyle efter dem, og en hidsig jagt går i gang. Ledet af Rubber Duck og skarpt forfulgt af politiet og medierne kører truckerne mod grænsen til New Mexico, mens flere og flere lastbiler slutter sig til konvojen.
Golfkrigen, 1991. Jack Starks overlever et pistolskud i hovedet, men får hukommelsestab. Og da han efter hjemkomsten til Vermont bliver beskyldt for mord, er der intet, han kan gøre… Han bliver indlagt på en lukket afdeling og udsat for en ny, kontroversiel behandlingsform. Stærkt påvirket af hallucinogene stoffer rejser han ud i fremtiden, hvor han møder Jackie. Hun gemmer på nøglen til den mørke fortid, Jack ikke kan huske… Og da hun opdager, at Jack er fire døgn fra sin dødsdag, må de sammen prøve at undgå det uundgåelige…
Jim samler en blaffer op. Det skulle han ikke have gjort. John Ryder er nemlig ikke bare bevæbnet, men også en bindegal voldspsykopat. Jim undslipper, men John forfølger ham gennem hele USA, mens han myrder løs til højre og venstre. Og politiet tror selvfølgelig der er Jim, der står bag.
Gerningsmanden bag et røveri af en pengetransport slipper af sted med fire millioner dollars. De er jaget vildt, så for at smugle pengene forbi politiets vejafspærring gemmer de byttet i en intetanende families bil. Snart aner familien uråd, men de har ingen idé om, hvor langt forbryderne er parate til at gå for at få deres penge igen.
FBI Agent Karl Helter and his partner Rebecca Lombardo are very close to busting a sex-trafficking ring. When they realize their investigation has crossed the path of a brutal serial killer, they team up with a FDLE agent to put an end to the infamous 'Truck Stop Killer'.
Loner Diane Ford is a truck driver with an 11-year-old son, Peter, whom she never sees, and that's fine with her. But, when Peter's father, Len, falls ill, he asks Diane to take care of their son for a while. Eventually, Diane reluctantly agrees, but she quickly realizes that caring for a child interferes with her independent lifestyle - and Peter isn't all that thrilled with the arrangement, either.
A poor young woman is recruited by a friendly couple traveling in an RV into becoming part of the dark world of truck stop prostitution.
The Story of Oddyseus and the Sirens placed in the countryside of France. Oddyseus is a trucker and his Penelope runs a café.
Acclaimed director Abolfazl Jalili offers a compassionate story of the young Afghan refugee who lives illegally in Iran. 14-year-old Kaim drifts to the Delbaran crossing on the Afghan-Iran border, where he finds work at a coffee shop frequented by truck drivers. He feels at home in this small oasis of friendliness, though the sounds of war can be heard in the background, violent bandits prowl the roads, and opium is everywhere. As we watch Kaim run from one task to another day after day, we soon realize that we are watching a boy who is being cheated out of his childhood.
An investigative journalist researches the biggest case of his life - the sudden disappearance of his wife.