An inspirational speaker becomes reinvigorated after meeting a lively woman who shakes up his mundane existence.

Dolores Claiborne was accused of killing her abusive husband twenty years ago, but the court's findings were inconclusive and she was allowed to walk free. Now she has been accused of killing her employer, Vera Donovan, and this time there is a witness who can place her at the scene of the crime. Things look bad for Dolores when her daughter Selena, a successful Manhattan magazine writer, returns to cover the story.

By following the lives of five Japanese individuals this documentary explores the problem of depression in Japan and how the marketing of anti-depressant drugs has changed the way the Japanese view depression. Marketing of anti-depressants did not begin in Japan until the late 1990s and prior to this, depression was not widely recognized as a problem by the Japanese public. Since then, use of anti-depressants has sky-rocketed and use of the Japanese word "utsu" to describe depression has become commonplace, having previously been used only by psychiatric professionals.

Following her boyfriend Felix's attempted suicide, Katherine attempts to bring him back to his normal way of life. However, after discovering a bottle of pills in Felix's possession, a confrontation emerges, making them question whether or not they can return to the way life had been before.