カリフォルニア州捜査局（通称・CBI）の犯罪コンサルタント、パトリック・ジェーン。元詐欺師で以前は自身を霊能者(サイキック)と偽り活躍していた。妻と娘を殺した宿敵レッド・ジョンを追うため、CBIのコンサルタントとなり、人間心理を巧みに操る観察眼と推理力を持つ「メンタリスト」として型破りな捜査で犯人を追う。

The world's leading deception researcher, Dr. Cal Lightman, studies facial expression, body language and tone of voice to determine when a person is lying and why, which helps law enforcement and government agencies uncover the truth. But his skills also make it easier for him to deceive others.

Clinical psychologist Dr Tony Hill's uncanny ability to see into the minds of murderers means he finds it difficult to distance himself from disturbing cases.

FBI agent Angela Clinton has the exceptional gift of knowing when someone is lying. She discovered this skill at age 14, when she learned her "average" American parents were actually spies. Attempting to right her parents' wrong, Angela is now working with the same agency that brought her parents down.

Crime drama based on the UK TV series about Gerry "Fitz" Fitzgerald, a brilliant but troubled criminal psychologist working alongside the Los Angeles police department.