Dr. Daniel Pierce, a neuroscientist and professor, is recruited to help the federal government crack difficult cases. His intimate knowledge of human behavior and masterful understanding of the mind give him an extraordinary ability to read people, but his eccentric view of the world and less-than-stellar social skills can often interfere with his work.

Serien kretsar kring Sydney Fox, en professor som reser över hela jordklotet i jakt på antika föremål för att lämna till museum eller dess rättmätiga ägare. Hon assisteras av den blyge och tafatta assistenten Nigel och ibland av den lite vimsiga sekreteraren Claudia. Hon hamnar ofta i en kamp mot andra skrupelfria kultjägare som inte drar sig för någonting i jakten på de värdefulla föremålen som ofta har övernaturliga krafter.

Alec Baker är en berömd professor i beteendevetenskap som använder sin förståelse för mänskligt beteende för att lösa avancerade fall – på sätt som ingen annan kan föreställa sig.

An alien who came to Earth 400 years ago is almost able to return to his own planet, but when he meets a famous actress, he doesn't want to go home.

Declan Dunn has a fascination with mystical phenomena that began when he was buried under an avalanche and given up for dead. After he miraculously survived, he committed his life to investigating miracles and the absolute proof of their existence. Now a professor of Anthropology at a leading Oregon university, Declan has the training, support staff and the opportunity to study the uncanny, inexplicable phenomena people call "miracles". With the help of Peggy, a skeptical psychiatrist, and Miranda, a research student, the three embark on a quest to explain what science cannot.

Pursuit of Happiness is an American sitcom that aired on ABC from October 30, 1987 to January 22, 1988.