An artist grows distant from his new wife as an irrational horror of premature burial consumes him.

Three tales of horror, isolation and insanity set in Mexico.

A crazed scientist invents a serum that induces a catatonic state in anyone who gets the injection. He uses the serum to paralyze his enemies, in order to bury them alive.

A traveler arrives at the Usher mansion to visit his old friend, Roderick Usher. Upon arriving, however, he discovers that Roderick and his sister, Madeline, have been afflicted with a mysterious malady: Roderick's senses have become painfully acute, while Madeline has become nearly catatonic. That evening, Roderick tells his guest of an old Usher family curse: any time there has been more than one Usher child, all of the siblings have gone insane and died horrible deaths. As the days wear on, the effects of the curse reach their terrifying climax.

Just after Isidore moves to France to study filmmaking, his best friend dies back in the US. Through documentary, performance, and animation, a ghostly portrait emerges, prompting Isidore to question his relationships with his parents and his boyfriend in Paris.

Salome goes out for another day at work, but not without bringing a definitive closure to a delicate occurrence.