A World War II submarine commander finds himself stuck with a damaged sub, a con-man executive officer, and a group of army nurses.

The Army nurses on Bataan need help badly, but when it arrives, it sure isn't what they expected. A motley crew, including a Southern belle, a waitress, and a stripper, show up. Many conflicts arise among these women who are thrown together in what is a desperate and ultimately hopeless situation.

During the start of the Pacific campaign in World War II, Lieutenant Janet Davidson is the head of a group of U.S. military nurses who are trapped behind enemy lines in the Philippines. Davidson tries to keep up the spirits of her staff, which includes Lieutenants Joan O'Doul and Olivia D'Arcy. They all seek to maintain a sense of normal life, including dating, while under constant danger as they tend to wounded soldiers.

With no other prospects, a World War I veteran puts the skills they taught him in the War to use.

Although released anonymously, as was the custom with all films produced by the Italian Navy, La Nave Bianca is the first feature-length effort directed by Roberto Rossellini; it is also very much the work of its co-writer and supervisor Francesco De Robertis. The film combines a documentary look at the Italian Navy during World War II with newsreel combat footage and a scripted love story performed by non-professional actors.