Blade er halvt menneske og halvt vampyr, og sammen med sin mentor, Whistler, modarbejder han de blodtørstige vampyrers kamp for verdensherredømme. Blade er samtidig drevet af sit ønske om at hævne mordet på sin mor, og han må derfor konfrontere den farlige Deacon Frost, som ved hjælp af en gammel vampyrguddom vil betvinge menneskene i et ultimativt blodbad.

Rocky, Colt and TumTum must battle an evil wealthy toxic waste dumper in order to save a local Indian tribe and their friend Joe. The 3 Ninjas must help find Joe's father and find a secret disk that contains evidence that could stop the toxic landfill that is destroying the Indian community. However the town is owned by the rich man and he controls the police and even the mayor. They must fight a motorcycle gang and renegade cowboys in this non-stop ninja adventure.

During a championship baseball match, the three brothers hear that their grandfather in Japan is in trouble, and head out to help him, conceding the match. When they arrive in Japan, they must use all their powers to defend him against his ancient enemy, who has returned to exact revenge.