Den retskafne irske læge Peter Blood bliver dømt til slaveri på Jamaica. Heldigvis undslipper han, og under navnet Kaptajn Blod gør den tidligere læge de karibiske farvande usikre for de spanske skibe. Undervejs smelter han pigehjerter og sætter skurke på plads.

I Mexico slutter en broget trio sig sammen for at redde indianerne fra en tyrannisk general. Nemlig en sherif, en bankrøver og en kvindelig revolutionær.

The film pivots around the local Norwegian doctor and his family. The doctor's wife (Ruth Gordon) wants to hold on to the pretence of gracious living and ignore their German occupiers. The doctor, Martin Stensgard (Walter Huston), would also prefer to stay neutral, but is torn. His brother-in-law, the wealthy owner of the local fish cannery, collaborates with the Nazis. The doctor's daughter, Karen (Ann Sheridan), is involved with the resistance and with its leader Gunnar Brogge (Errol Flynn). The doctor's son has just returned to town, having been sent down from the university, and is soon influenced by his Nazi-sympathizer uncle. Captain Koenig (Helmut Dantine), the young German commandant of the occupying garrison, whose fanatic determination to do everything by the book and spoutings about the invincibility of the Reich hides a growing fear of a local uprising.

Soldier of fortune, Monroe Bieler, is sent to dole out some American-style justice when the wife and child of an African president are kidnapped by terrorists.