弗兰西斯·安德伍德是一位极具政治野心的南卡罗来纳州民主党众议员、众议院多数党党鞭。他帮助加勒特·沃克赢得大选成为第45任美国总统，而沃克作为回报则许诺将任命他为国务卿。然而，在沃克宣誓就职之前，白宫幕僚长琳达·瓦斯奎兹却告知安德伍德，称总统希望将他留在国会推动法案通过，因而将不会提名他作国务卿。安德伍德对总统的背叛之举愤怒不已，他决定单干倒戈，逐步实现自己的总统梦想。

《副总统》是HBO推出的一部喜剧，镜头对准了一个虚构的美国副总统的办公室。前参议员Selina Meyer接受任命，担任美国副总统一职。然而这份工作与她想象中的完全不一样。该剧聚焦Meyer和她的团队，她们希望在任职期间有所作为，留下政绩，而不要受深陷华盛顿的政治游戏中。

Mackenzie Allen has a lot on her plate -- she has twin teenagers, a 6-year-old at home and an ambitious husband at the office, and she is about to become the first female president of the United States. Before that happens, however; Mackenzie, who serves as vice president, has to decide whether or not to go against the dying wishes of the current president, who has asked her to step down and let someone "more appropriate" fill his shoes in the Oval Office. Not only does the president want her to resign, so does the entire party that elected her in the first place. But when the moment of truth arrives, Mackenzie isn't willing to be a mere footnote in history. Instead of allowing her detractors to keep her down, she decides to trust her instincts and accept the most powerful job in the world.

一个能干的秘书和一个自恋的老板坠入爱河，同时揭开了一段不堪回首的往事，这让他们怀疑自己的感情是真实的还是共同创伤的结果。

该剧改编自郑庆允的2013年同名人气网漫，讲述拥有完美外貌和过人实力的财团副会长李英俊，他的个人秘书金美苏是唯一帮他解决麻烦的人。工作9年，一直在李英俊身边如影随影，能力满分的她, 有一天突然决定要辞职，让李英俊下定决心要用尽方法留住她…

Hidden from the view of the public - and even from the President - there is a top secret agent who is trained and ready to serve, deployed only at the careful discretion of the Vice President.