Parker er den mest dristige, grundige og hensynsløse tyv i branchen. Han er ekspert i planlægning og udførelse af tilsyneladende umulige røverier. Det eneste, han forlanger af sit team er ubetinget loyalitet, samt at hans plan følges til punkt og prikke. Men da det sidste job ender med et dødsfald på grund af uforsigtighed, afslår Parker at deltage i gangsterchefen Melanders næste store kup. Melander og hans bande er dog ikke villige til at acceptere et nej, så Parker bliver sønderbanket og efterladt til at dø. Han overlever dog mod alle odds, og sværger en grusom hævn mod dem, der forrådte ham.
Den tidligere racerkører Peter Roberts (Thomas Jane) tror det bliver en helt almindelig, stille dag, da han møder på arbejde til hans første klient. Men Mr. Keller (John Cusack) har andre planer. 'Kan vi lige stoppe ved banken?' spørger han uskyldigt. For sent går det op for Peter, at Mr. Keller er bankrøver! Pludselig har Peter en pistol i ansigtet og bliver tvunget til at være flugt-chauffør! Med politiet og - for det ikke skal være løgn - mafiaen i hælene, må de to stikke af i en vild jagt igennem Gold Coast, Australien.
It is written among the limitless constellations of the celestial heavens, and in the depths of the emerald seas, and upon every grain of sand in the vast deserts, that the world which we see is an outward and visible dream, of an inward and invisible reality ... Once upon a time there was a golden city. In the center of the golden city, atop the tallest minaret, were three golden balls. The ancients had prophesied that if the three golden balls were ever taken away, harmony would yield to discord, and the city would fall to destruction and death. But... the mystics had also foretold that the city might be saved by the simplest soul with the smallest and simplest of things. In the city there dwelt a lowly shoemaker, who was known as Tack the Cobbler. Also in the city... existed a Thief, who shall be... nameless.
A Mongolian Historical Treasure is identified in Vietnam, and four thieves are given orders to steal the valuable.
An off the grid, ex Hong Kong hitman loner, Jimmy Hayabusa lays low in Chicago and develops a budding romance with his apartment building neighbor. While his precision planning may never have let him down before, his new love may have inadvertently landed him in the hands of the "Syndicate", the City's ruthless organized crime gang.