在無法無天的美國與墨西哥交界區邊界，滿懷理想的聯邦調查局探員凱特 被迫進入了查緝國際毒品走私的殘酷世界。凱特奉命加入一支由經驗老到的麥特 所帶領的聯邦政府特種部隊，目標是逮捕一位勢力遍及中美洲、全墨西哥最惡名昭彰的販毒集團老大。 由於面對的是無惡不作，無論毒品交易、販賣人口、殺人曝屍等犯罪活動通通都沾手，殘暴無比的犯罪集團，步步為營的麥特找來曾在毒梟身邊臥底，卻有謎樣過去的前特工人員亞歷 擔任顧問。凱特跟著亞歷和麥特一行人，透過一次次的行動斬獲，一步步靠近固若金湯的毒梟大本營，然而，越是逼近虎穴，凱特越感受到亞歷所採取的實事求是實戰手段，越為黑白不明。不斷震撼著她所能承受的暴虐極限，更衝擊著她本原所相信的所有執法信念。

薩羅阿門達里茲是一名來自埃爾帕索的同性戀業餘摔角手，在創造了 “反串摔角手”卡珊卓這個角色後，他一躍成為國際巨星。在這個過程中，他不僅顛覆了充滿男子氣概的摔角界，也顛覆了自己的人生。

Two teenage Mexican-American loners in 1987 El Paso explore a new, unusual friendship and the difficult road to self-discovery.

A Vietnam veteran, Charles Rane, returns home after years in a POW camp and is treated as a hero. When thugs invade his home to steal the silver coins he received for his service, they mangle his hand and leave him and his family for dead. Rane survives and becomes obsessed with getting revenge. Aided by his loyal friend Johnny Vohden, Rane, now wielding a hook for a hand, sets out on his mission of vengeance.

A documentary film crew follows Bernie Rosenblum to the El Paso, Texas ranch where he worked in 1966 on what is arguably the worst movie of all time.

Recovering from a toxic relationship, James Savage confronts both his inner demons and enigmatic ex-girlfriend, Janet, before she executes a world-ending ritual. James navigates her reality-bending universe of ethereal monsters while facing the truth of his own addictions and skewed sense of self-worth. James learns that the only route to love is through healing.

In El Paso, Texas, Sarah finds herself in a very bad debt to an even worse cartel. To pay it off, she will have to find some missing money with the help of a mysterious stranger.