Malpertuis is the name of an old, rambling mansion which is in reality a labyrinth where characters from Greek mythology are imprisoned by the bedridden Cassavius. He manages to keep them, as well as his nephew and niece, prisoners even after his death, through a binding testament. As Jan, the nephew, unravels the mystery, he discovers that he cannot escape the house because Malpertuis is far more significant than he was led to believe.

Un grup de científics emprèn un viatge espacial de més de dos anys a la nau Prometheus cap a un remot planeta, amb l’objectiu de trobar resposta sobre l'origen de la vida a la terra, però aviat s'adonen que no estan sols.

Mary Wollstonecraft coneix el brillant poeta Percy Shelley. L'atracció que es desperta entre tots dos marcarà per sempre el destí de la creadora d´una obra immortal: "Frankenstein de Mary Shelley".