Den rapkæftede radiovært Grant Mazzy (Stephen McHattie) er blevet henvist til en lille lokal station i byen Pontypool, hvor han forhåbentlig ikke laver alt for meget ballade. Det tegner til at blive en helt almindelig kedelig aften, men så begynder der at ske noget mystisk. Spredte rapporter kommer ind fra forskellige steder i byen: Folk går amok i gaderne… De angriber hinanden… Det er som om vreden spreder sig. Isoleret på radiostationen forsøger Grant, hans producer og hans tekniker desperat at danne sig et overblik over situationen. Hvad det end er, så kommer det tættere og tættere på dem!

Honest and straightforward small-town Shirlee Kenyon chucks her boyfriend and heads for Chicago. Accidentally having to host a radio problem phone-in show, it is clear she is a natural and is hired on the spot. But the station insists she call herself Doctor, and as her popularity grows a local reporter starts digging for the truth. Problem is, the more he is around her the more he fancies her.

A deeply-disturbed priest goes on a murderous night-time rampage across America's highways.

A housewife (Perri Cummings) who becomes infected with the vitriolic words of a bigoted talk radio host, in this commentary on the culture of fear and distrust spread by the media post-9/11. Created for Drafthouse Films’ THE ABCS OF DEATH ‘26th Director’ competition.

Lou spent so many years listening to talk radio that he was left wondering whether there was actually any reason to live.

Benjamin tells his ex-girlfriend, Angie, that he joined a cell of left-wing terrorists to get revenge on her former boss, who owns a right-wing radio station. His story blends conceptual artists, amateur theatre troupes, hallucinogenic vinyl record and other magical powers. All that nonsense leave Angie wondering if he made that up only to win her back.

A group of terrorists take a radio disk jockey and his wife and child hostage in order to get their manifesto out to the world.