Krajem osamnaestog stoljeća, bivši istraživač i rekreativna pijanica Bartholomew Hunt (Chris Farley) i povučeni Leslie Edwards (Matthew Perry) predvode razularenu ekipu otpadnika i ništarija preko neistraženog teritorija od rijeke Mississippi do Pacifika. Njihovi suparnici Lewis i Clark u priličnoj su prednosti, ali dvojica se junaka ne predaju, putem doživljavajući brojne nezgode.

13-year-old Gunther Strobbe grows up surrounded by alcohol, trash and his completely useless father and uncles. Slowly but surely, he's being prepared for the same hapless life. Can he defy his destiny?