Seminary student Michael Kovak reluctantly attends exorcism school at the Vatican. While he’s in Rome, Michael meets an unorthodox priest who introduces him to the darker side of his faith, uncovering the devil’s reach even to one of the holiest places on Earth.

Whatever Works explores the relationship between a crotchety misanthrope, Boris and a naïve, impressionable young runaway from the south, Melody. When Melody's uptight parents arrive in New York to rescue her, they are quickly drawn into wildly unexpected romantic entanglements. Everyone discovers that finding love is just a combination of lucky chance and appreciating the value of "whatever works."

After making a psychologically compromising decision, a young woman faces a vividly strange reality.