I Los Angeles prøver Ronna og Claire desperat at finde en måde at betale huslejen. Simon og Marcus stjæler en bil under en festlig nat i Las Vegas. Adam og Zack bliver involveret i en kaotisk politi-aktion mod stoffer. Alle bliver i løbet af et døgn forbundet gennem en fejlslået narkohandel og alle er ude hvor de ikke kan bunde.

Jane, a struggling but perpetually stoned actress, has a busy day ahead. She has several important tasks on her list, including buying more marijuana. Even though she already has a good start on the day's planned drug use, she eats her roommate's pot-laced cupcakes and embarks on a series of misadventures all over Los Angeles.

Brian comes under the addictive spell of a parasite with the ability to induce euphoric hallucinations in its hosts.

An educational film from 1967 designed to scare teenagers away from illegal drugs

Cocaine has always gotten a bad rap, and for a reason. It is a drug used by the rich and the poor legally and illegally, Mexican cartels fought over it with Colombia once associated with the brutal cocaine wars, and a source of tension between the American and Mexican borders on the people who are illicitly bringing in cocaine from one side of the border to another and will do anything to do it. So it can be surprising at times to the viewer throughout the course of the documentary special, that it was never always like this.

A man wants to fly in the air like his friend

Documentary about human experiments conducted at the Veterans Hospital in Palo Alto, California in the 60's, scientific studies about the effects of pure THC.

First timer Aaron goes to buy from a sketchy dealer, when he's invited inside a weird friendship starts to blossom. Until everything begins to spiral out of control.

Heroin anti-drug educational film