L'adorable Sulley et son acolyte pince-sans-rire Mike Wazowski forment la meilleure équipe effrayante de MONSTRES, INC., l'usine de traitement des cris de Monstropolis. Quand une petite fille nommée Boo erre dans leur monde, ce sont les monstres qui ont peur d'elle, et c'est à Sulley et à Mike de la garder hors de vue et de la ramener à la maison.

L'archéologue Indiana Jones est obligé de fuir un cabaret de Shanghai après une négociation houleuse. En compagnie de la chanteuse Willie Scott et du petit Short Round, il se retrouve sur un glacier himalayen, dans un village dont une secte a dérobé le diamant magique et enlevé les enfants afin de les sacrifier.

As the baby boom commences, and with the delivery service overworked, Porky Pig and Daffy Duck are placed in charge of a baby preparation factory, where they help the stork keep up.

After getting into a scuffle with his boss and some co-workers, an orange packer tries to help another co-worker, only to wind up in a conflict with him as well. Trying to elude his boss, he heads inside the packing house, and visits with the women who are packing fruit into cases. Then he heads to a storage area, and tries to use the machinery to escape his pursuers.

In a futuristic, antiseptic food factory, workers select healthy chicks, while the rejects are carried along a conveyor belt until they are crushed by a mallet and drop into a garbage bin. A single black chick appears among the yellow and is shoved toward the garbage bin. Before the mallet strikes, the gasping chick rebels.