Tough-as-nails vampire hunter Derek Bliss is on the hunt for "suckers" in the heart of Mexico when he receives a new assignment from a mysterious client. Thrown together with a group of slayers, including sexy Zooey, who may or may not be one of the undead. Derek and company are up against a growing number of fast-moving, bloodthirsty vampires and their elusive and powerful leader.

A top-secret experiment spawns two highly intelligent life-forms: Einstein, a golden retriever with an IQ of 175; and The Outsider, a deformed monstrosity that exists to kill... and avenge its creators. When the Outsider escapes into the jungles of South America, the government sends in some ex-military convicts to catch the beast. But what starts out as a high-speed chase ends up in bloody carnage. Only Einstein knows the Outsider's motives, and only the canine can outsmart the creature. Now, it's a battle of beasts as man's best friend confronts man's worst nightmare.