红色小狗长成了一只 25 英尺的巨犬,小女孩和舅舅必须保护他们可爱的新宠物免受邪恶基因公司的侵害。
Lester and Orville accidentally launch a rocket which is supposed to fly to Mars. Instead it goes to New Orleans for Mardi Gras. They are then forced by bank robber Mugsy and his pal Harry to fly to Venus where they find a civilization made up entirely of women, men having been banished.
Fearing that he costs too much to feed, Clifford decides to join a traveling carnival so he can enter a talent contest in hopes of winning a lifetime supply of Tummy Yummies treats. Joined by his friends Cleo and T-Bone, Clifford meets up with Shackleford the High-Flying Ferret and Rodrigo Chihuahua of Steel, as they work together to turn a broken-down act into a record-breaking show.