11 episodi con ambientazione fissa compongono un progetto iniziato nel 1986 e che attraverso gli anni giunge infine a compimento. Come in tutti i film ad episodi, sta allo spettatore eleggere i suoi favoriti, e in C&C c'è di che scegliere. Tanti grossi nomi prestano il loro volto all'amico Jarmusch, in un carosello di personaggi che hanno in comune tre cose: fumano, bevono caffè e parlano di cose assolutamente prive di senso. La palma d'oro per il dialogo più improbabile a Tom Waits e Iggy Pop, due tra gli individui più "storti" e indispensabili del nostro tempo. Per quanti condividono e vivono l'idea che caffè+sigarette sia il matrimonio più riuscito di sempre, potrebbe diventare un vero manifesto.
La figlia di un riccone, viziata e legata da morboso affetto al padre, fa innamorare un giovane infermiere strappandolo alla dolce fidanzata. Un giorno il padre e la matrigna della fanciulla muoiono in un incidente e il giovane sospetta che sia stata la ragazza a provocarlo. Difatti è così. E la pestifera ereditiera ci riprova: dopo aver ammazzato anche il suo innamorato, si suicida.
A patient in an hospital dies under mysterious circumstances. The attending doctor Frank Holt gets under suspect - he'd been fired already from his last position due to malpractice. For his defense he investigates with help of doctor Anna Lang. Soon they find out that half of their colleagues were betting on the patient's diagnosis - was someone trying to increase his chances? But when Frank's friend, dissector Mary Connor, becomes deadly sick, he suspects there's even more to it.
Dora, a young woman at the center of an unusual murder trial, is subjected to a psychiatric evaluation, and as the tests become more personal — and frightening — she begins to question the true motives of her doctor and is forced to live through the recreations of her past.
Crime drama starring Richard Cromwell as a young medic who becomes the private physician to an underworld gang.
Emergency medicine intern Margaux can no longer stand it. During another very hectic and patient-filled shift, she forgets a homeless woman on a stretcher who then dies. Shocked Margaux has no choice but to continue working. But suddenly, her body starts sweating blood uncontrollably.
Traumatised by her daughter's death a Ukrainian nurse takes retribution, but is conflicted by her faith and unprepared for the consequences.
Judith is a doctor who is very committed to her profession. Aiming to become a cardiologist, she performs part of her residency in a chronically understaffed hospital emergency room. During a particularly difficult shift, she makes a mistake that causes the death of a patient. Judith is devastated and doubts whether she is suited to the profession. Her fellow doctors, including her partner Mark, advise her to just carry on as before. While Judith’s actions are investigated, she is assigned to ambulance duty. Being in a new environment and having some distance to the clinical routine allow her to see things in a new light.
The tree surgeon (a donkey) races to the giant sequoia, which isn't feeling well. His techniques, though, seem better suited to treating a person.