Ajan läpi lähetetty samurai taistelee pahaa, muotoa muuttavaa velhoa vastaan palatakseen kotiin ja pelastaakseen maailman tässä Genndy Tartakovskin kekseliäässä ja tyrmäävän kauniissa animoidussa tarinassa.
In the near future, planet Earth is permanently altered following the sudden—and tumultuous—arrival of seven unique alien races. In the boom-town of Defiance, the newly-formed civilization of humans and aliens must learn to co-exist peacefully.
MegaTokyo 2033: Tokyo was left flattened as a result from a great earthquake.
A new city, MegaTokyo, was then recreated due in no small part from the aid of a multi-million dollar company, Genom Corp. Genom created and mass-produced biomechanical creatures called Boomers to aid in the restoration of MegaTokyo.
When the Boomers began to run out of control, the ADPolice at first tried to stop them, but they proved to be far more difficult to deal with than was first imagined.
Under the ever looming Boomer threat, a group of four girls from varying degrees of society banded together. Calling themselves The Knight Sabers, they were the only ones with enough firepower and resourcefullness to defend the fledgling MegaTokyo from Genom and it's berserk Boomers.