Dette er historien om Butch Cassidys skæbne efter han og The Sundance Kid stødte ind i den bolivianske hær i 1908, i slutningen af Butch Cassidy and the Sundance Kid. Nu går han under navnet James Blackthorn. Han er blevet gammel og drømmer bare om at se sit hjem en sidste gang. Derfor bevæger han sig ud på en lang rejse, og undervejs møder han en ung bankrøver, der får trukket ham med på et sidste eventyr.
Brady Sutton returns from three years in prison and tries to go straight. One a member of the Butch Cassidy gang, he is still suspected of being cahoots with them. When Cassidy and his men rob the bank, he is blamed. Escaping from the townspeople, he once again joins up with Cassidy to wait for a chance to help bring him in.
Pat Garrett arrives in Abilene where he catches five of Butch Cassidy's gang. He calls in Wyatt Earp and Bat Masterson and they learn there is a half million dollar shipment of money arriving by train and Cassidy is amassing enough men to take it.
Set against the backdrop of the late 1800s, Bub Meek helplessly watches his best friend rise to infamy as an outlaw, known only as Butch Cassidy, the leader of the Wild Bunch.
The historical account of outlaws Butch Cassidy and the Sundance Kid, whose turn of the last century exploits made headlines, led them to be pursued by Pinkerton detectives hired by the railroads, and inspired a hit 1969 film.