Sebastián, an actor known for just one role he played years ago, is about to get engaged, but life has other plans for him. Just when his life seemed to be all mapped out, he is thrown back in the fold with his long time friends who are bad at relationships. All of the sudden, he goes back to the life he left almost 10 years ago: being single.

Akira Fudo learns from his best friend Ryo Asuka that demons will revive and reclaim the world from humans. With humans hopeless against this threat, Ryo suggests combining with a demon. With this, Akira becomes Devilman, a being with the power of demon but with a human heart.