Efter at Kirsty Cotton fik sin familie udslettet af klosterbrødrene, blev Kirsty sendt til et sindssygehospital, hvor hun der kommer under Dr. Channards behandling. Ingen tror dog på Kirsty. Hospitalets leder Dr. Channard forstår dog hurtig sammenhængen, i det han har kendt til de kræfter, som Frank Cotton havde haft med at gøre. Channard havde nemlig længe ledt efter selvsamme kræfter. Kirsty får hjælp fra en uventet kant, da en af hospitalets ansatte, Kyle, vælger at tro på Kirstys historie, og beslutter sig for at hjælpe hende. Han tager hen til Dr. Channard og i hans hus, finder han bevis for Kirstys historie.

Denne skræmmende og bizarre DC Elseworlds-historie er en blanding af Batmans verden og H.P. Lovecrafts kosmiske horrorfiktion.

Boris Karloff spiller hovedrollen som en af filmhistoriens mest legendariske monstre i denne film, som af mange opfattes som alletiders største gyserfilm nogensinde. Dr. Frankenstein (Colin Clive) vover at eksperimentere med liv og død ved at skabe et menneskeligt monster (Karloff) af ligdele. Instruktøren James Whales fortolkning af Mary Shelleys roman og Karloffs medfølende portræt af Frankenstein uhyret, der søger sin egen identitet, gør Frankenstein til et mesterværk ikke kun i sin genre, men for evigt i filmhistorien.

In the 1960s, a nurse's last day on her job is ruined when a doctor inadvertently creates a cyst monster that terrorizes the office.

After a pawn shop robbery goes askew, two criminals take refuge at a remote farmhouse to try to let the heat die down, but find something much more menacing.

After Malukan immigrants engage in a string of corpse mutilations at various New York City hospitals, a doctor and a morgue assistant travel to the Maluku Islands to investigate.

An insane surgeon's obsession with an actress leads him to replace her wounded pianist husband's hands with the hands of a knife murderer--hands which still have the urge to throw knives.

I 1925 myrdes en række læger på makaber vis. Politimanden Trout øjner en sammenhæng, idet drabsmetoderne alle synes inspireret af Egyptens ti plager. Han mistænker dr. Phibes, en læge og videnskabsmand, som ellers var formodet død i et biluheld. Den vansirede Phibes er gal af sorg, efter at hans kone døde under en operation, og nu tager han grusom hævn over de læger, som behandlede hende.

A scientist working on cures for rare afflictions, such as a bone softening agent made from molds to allow him to correct the spinal deformity of his nurse, finds the physical causes of lycanthropy in wolf-man Larry Talbot and of vampirism in Count Dracula, but himself becomes afflicted with homicidal madness while exchanging blood with Dracula.

Dr. Hohner, theatre physician at the Vienna Royal Theatre, murders his mistress, the star soprano when his jealousy drives him to the point of mad obsession. Ten years later, another young singer reminds Hohner of the late diva and his old mania kicks in. Hohner wants to prevent her from singing for anyone but him, even if it means silencing her forever.

University professor George Kingsley is struck by gangsters while crossing the street, leaving him with brain damage and one of the gangsters, Cannon, paralyzed. Kingsley's friend Dr. Sovac attends to both men, and when Cannon offers him a reward for aiding his recovery, Kovac transplants part of Cannon's brain into the dying Kingsley's skull, creating a dual personality.

A brilliant but deranged neurosurgeon becomes obsessively fixated on a judge's daughter. With the help of an escaped criminal whose face he has surgically deformed, the mad man lures her, her father, and her fiancé to his isolated castle-like home, where he has created a torture chamber with the intent of torturing them for having 'tortured' him.

A severely injured man and woman awake in an abandoned sanitarium only to discover that a sadistic caretaker holds the keys to their freedom and the horrific answers as to their true identity.

En gruppe studerende i London sætter sig for at bevise, at overnaturlige fænomener er en skrøne. Deres forsøgsperson, Jane Harper, lider af hukommelsestab og menes at være besat. Men efterhånden som eksperimentet skrider frem, oplever de studerende flere og flere uforklarlige hændelser. Måske er der alligevel mere mellem himmel og jord?

Dr. Bernard Adrian is a kindly scientist who seeks to cure a young woman's polio. He needs human spinal fluid to complete the formula for his experimental serum. Meanwhile, a vicious circus ape has broken out of its cage, and is terrorizing the townspeople. Can there be a connection?

An unnamed doctor has always had everything he's ever wanted, but that has only made him develop more extreme and depraved needs. He kidnaps a young couple in the prime of their life together and forces them into a game of torment that slowly extinguishes their hopes for survival.

When Chris and Andy order a model from an escort service, they find that something is unnaturally wrong with Natasha, something deadly wrong.

Dr. Bill Cortner and his fiancée, Jan Compton, are driving to his lab when they get into a horrible car accident. Compton is decapitated. But Cortner is not fazed by this seemingly insurmountable hurdle. His expertise is in transplants, and he is excited to perform the first head transplant. Keeping Compton's head alive in his lab, Cortner plans the groundbreaking yet unorthodox surgery. First, however, he needs a body.

The eminent Dr. Phibes awakens from a decade of suspended animation and heads to Egypt with the corpse of his dead wife, which he intends to resurrect by murdering people in strange and heinous ways.

When his experiments into a powerful new anesthetic go hideously awry, respected physician Dr. Jekyll transforms into the hideous Jack Hyde. As his wife Elisabeth passes her time in charitable work, rehabilitating the district's fallen women, Hyde is drawn into an escalating cycle of lust and murder that seems to know no bounds.