Trinity series star Bud Spencer returns to the Wild West in director Michele Lupo's comic tale of an outlaw drifter, Buddy, who is mistaken for a doctor after his Indian companion inadvertently steals a bag of surgical instruments. When a band of murderous outlaws attempts to overrun the small town Buddy is passing through, the presumed medico shows that his true talent is cracking skulls. Music is composed by Ennio Morricone.

A former astronaut helps a government agent and a police detective track the source of mysterious alien pod spores, filled with lethal flesh-dissolving acid, to a South American coffee plantation controlled by alien pod clones.

Savino La Gastra discovers his wife Celeste has a liaison with an architect: Andrea. Even if also Savino has a story with Elvira, a judge's wife, he decides anyway to ask to a mobster to kill his wife. In the mean time Celeste is organizing a surprise party for Savino's birthday, and that day things start to get complicated. First Savino kills accidentally the mafia killer in charge to kill Celeste; second his lover Elvira arrives to the party with the judge... not to mention the police and the mafia Don...

A meek accountant buys himself a gun and finds out he's a natural marksman. After the friend who introduced him to shooting is killed by gangsters, he seeks revenge.

Alberto deceived by his wife, goes to some place in the mountains to escape. There he meets a woman who was there for the same reasons that he was.

Claudia, Rita, and Caterina are three friends who live in a conservative Italian town and lead seemingly neat and respectable married lives. One day, they are summoned to the notary public's office and learn that Anna, one of their peers in high school who got a bad name as a "whore" in the town because of them and was forced to leave is now dead. Furthermore, she had amassed a great fortune abroad and decided to bequeath it to the three. However, she has a strange condition: Claudia, Rita, and Caterina should cheat on their husbands within three days and provide photographic evidence or else the inheritance will be donated to the retirement home.

A low rank journalist at Tribuna Sera newspaper receives a letter one day. His correspondence contains a serial killer's letters, which he exploits.