A novelist's wife and son see him changed by an apparent encounter with aliens in the mountains.

Jobe Smith är en vuxen man med en 6-årings intelligens. Han försörjer sig på att klippa folks gräsmattor och hjälpa till i kyrkan. Vissa i staden drar fördel av hans mentala tillstånd och både hånar och slår honom. Den hängivne vetenskapsmannen Dr. Angelo försöker att öka chimpansers intelligens med hjälp av virtual reality. När Angelos uppdragsgivare vill stimulera apornas aggressiva instinkter, hoppar han av för att fortsätta på egen hand. I Jobe finner han den perfekte försökskaninen. Jobes hela värld förändras. Äntligen kan han försvara sig mot sina plågoandar. Men något går snett.

When a group of people from different walks of life converge in a Hungarian castle situated in Budapest which has been sealed for 500 years, they bring with them a werewolf which slowly begins to cut their numbers down.

When his experiments into a powerful new anesthetic go hideously awry, respected physician Dr. Jekyll transforms into the hideous Jack Hyde. As his wife Elisabeth passes her time in charitable work, rehabilitating the district's fallen women, Hyde is drawn into an escalating cycle of lust and murder that seems to know no bounds.

Gary Brandner's horror novels come to life again in this direct-to-video sequel to "The Howling." A number of vicious murders occur in a small California town after a motorcycle-riding stranger arrives. The gruesome slayings look disturbingly like the work of a werewolf. Meanwhile, in another nearby town, police are hot on the trail of a killer they believe is a werewolf. This is "Howling" with a country-western angle.