A novelist's wife and son see him changed by an apparent encounter with aliens in the mountains.

Naukowiec-informatyk, dr Lawrence Angelo, prowadzi badania nad rzeczywistością wirtualną. Rezygnuje jednak z pracy dla agencji rządowej i eksperymentów na szympansach, gdy szefostwo usiłuje przeforsować nowy projekt, polegający na zwiększeniu agresji u zwierząt. Naukowiec kontynuuje badania na własną rękę. Tym razem "królikiem doświadczalnym" staje się Jobe Smith, niedorozwinięty ogrodnik z sąsiedztwa, kosiarz trawników. Nowy eksperyment przynosi zdumiewające wyniki.

When a group of people from different walks of life converge in a Hungarian castle situated in Budapest which has been sealed for 500 years, they bring with them a werewolf which slowly begins to cut their numbers down.

When his experiments into a powerful new anesthetic go hideously awry, respected physician Dr. Jekyll transforms into the hideous Jack Hyde. As his wife Elisabeth passes her time in charitable work, rehabilitating the district's fallen women, Hyde is drawn into an escalating cycle of lust and murder that seems to know no bounds.

Gary Brandner's horror novels come to life again in this direct-to-video sequel to "The Howling." A number of vicious murders occur in a small California town after a motorcycle-riding stranger arrives. The gruesome slayings look disturbingly like the work of a werewolf. Meanwhile, in another nearby town, police are hot on the trail of a killer they believe is a werewolf. This is "Howling" with a country-western angle.