Miriam Monroe and John Conrad are two young scientific workers who, independently of each other, have discovered a chemical called exonite. Miriam discovered it while searching for a cure for cancer, while Conrad used it as a basis for a powerful explosive.
John Wheeler (Warren Cook) gets himself in some financial hot water and needs to prove that he is half owner of some land in Canada. But the only person with a copy of the deed is Jean Corteau (Edwin Carewe, who also directed), and Corteau has gone up to the property and decided to claim all of it for himself.
One day Coventry Petmore leaves his wife and child to go out in the world and fight the social evils of divorce and loveless marriage. Circumstances lead him to the home of Judge Mitchell, where the judge's son, a minister, and his wife Beatrice reside. The minister does not believe in expressing affection to his wife, and Beatrice becomes enamored of her chauffeur Larry Price.
Old Silas Blackburn, a wealthy recluse, lives alone with his butler and his ward Katherine. One night, Katherine discovers Silas murdered in the room where three generations of Blackburns have mysteriously died. Silas' grandson Robert, whom Katherine loves, comes to visit the next day, suffering from amnesia.
When his friends decide that "Happy Jack" Lewis needs a wife, they place an ad in the paper for one. Glad Mason replies and sends her picture. Jack's pals decide she is the one, and after he sees her picture, Jack thinks so too -- until the saloon proprietor points out that maybe she doesn't look anything like her photo. In fact, she could be an old hag!
In this action-packed serial, government agent Quentin Locke infiltrates a corrupt patents company, only to run into the gleaming terror of its robot protector, the Automaton. In order to save the beautiful Eva Brent and find a cure for the dreaded Madagascar Madness, Locke suffers an inhuman array of tortures and physical restraints. He is chained, tied with barbed wire, padlocked in a crate and thrown in the water, tied beneath a descending elevator, strapped to an electric chair, and bound in an elaborate Oriental torture chamber.
William Baldwin, ruined in business by his partner, John Blaisdell, implores Blaisdell's aid, and receives in answer a five-dollar bill across the face of which is written, "Spend this for a gun and use it on yourself."
Captain Mills is jealous of Jim Clifford, his fellow officer at the British War Department, so he steals an important document in an attempt to make Clifford look bad. Clifford has to undergo quite a bit to get the papers back, and his adventures take him to several fancy weekend parties, including one on a yacht, which wrecks. He discovers that Mills gave the document to Grace Weston, who doesn't realize what she's got.
After his wife has run off with another man, New Yorker Bide Bennington decides to stay in Europe. After hearing of his wife's death years later, he returns home but finds it lonely there and heads West. While he is gone his house is robbed, and the leader of the crooks, Richard Glendo, leaves Bennington's coat and identification on an East River pier. The newspapers pick up on this and announce Bennington's "suicide." Since he is now officially deceased, Bennington decides to start life all over again -- but first he must foil a scheme by a gang of con artists, who have forced pretty Constance Brent to pose as Bennington's widow so that they can lay claim to his estate.
Cyril Hamilton is a chicken-hearted easterner who heads west. He makes up for his past misdeeds by rescuing a Cavalry colonel's daughter Marcia West from Mexican bandidos.
Actress Jane Carleson has three admirers: Henry Strong (a millionaire), Hamilton Ross (a chemist), and Murray Campbell (a district attorney). When Jane weds Campbell, Ross writes an anonymous letter to Campbell, warning him that Strong is after his wife.
Wealthy clubman Richard Dorian is a lighthearted soul who can't seem to take anything seriously, including his wife. Even when they decide to divorce, he meets the lawyers with a smile. When one of the attorneys suggests a charge of brutality, Mrs. Dorian points out that it is ludicrous. Dorian offers to have a party on his yacht, during which he will try very hard to be brutal to her to give her grounds for the divorce. Among the partygoers are Mrs. Dorian's guardian and Morgan, a smuggler who is buying the yacht. The guardian, who has squandered Mrs. Dorian's money on the stock market, kills himself. Dorian thinks that his wife killed him, gallantly takes the blame himself, and dives overboard. He becomes a tramp and is shanghaied by Morgan's men to become a stoker on his former yacht. Dorian's steward, Puck, is still onboard, and he tells Dorian that the guardian committed suicide.
Young Jim takes over from his father, political boss Jim Gordon Sr. As ruthless and unfeeling as his dad, Young Jim blocks the efforts by a crusading newspaper to bring about reforms in the city's tenement district. But he comes to regret his intransigence when his father is ruined financially.
Olive Muir, a haughty society girl, objects when Alice Prentice, a girl of lower station, comes to visit her family. After Alice's drunken father comes to visit the Muir home, Olive learns to her horror that she is adopted and that Prentice is her real father.
Steve, a young college chap who has been unfortunate in his business career, after a life of dissipation, concludes that life is not worth living and contemplates suicide.
Thrown out of his dad's house without a penny to his name, playboy J. Dabney Barron is told not to return until he has proven that he can keep a job for an entire month. After several false starts, our hero is hired to keep flighty heiress Betty Arden out of trouble. He not only succeeds but manages to get his hands on a valuable jewel that has long been coveted by his father.
Snobbish attorney Charles 'Beauty' Steele loses his wife due to his drinking and his airs at the same time that his brother-in-law absconds with funds belonging to one of Steele's clients. In search of the thief, Steele is attacked and left for dead. He is rescued by a kindly couple, but suffers from amnesia. He starts life afresh and is happy, until the return of his memory sends him back to resolve his old involvements.