Comedian Harmonists tells the story of a famous, German male sextet, five vocals and piano, the "Comedian Harmonists", from the day they meet first in 1927 to the day in 1934, when they become banned by the upcoming Nazis, because three of them are Jewish.
The unscrupulous bar owner Otto Grolbek hires the masseur Janos Klewe to murder his landlady. He then wants to inherit her and get his hands on some urgently needed money. But things turn out differently than planned: Janos is killed during the attempted murder in Portugal and Vera returns to Germany terrified. Now Otto has to commit the crime himself and kills his landlady. He disguises the crime perfectly, but has not reckoned with Inspector Mungowski's subtlety ...
After Sumsemann the beetle loses one of his arms to a troll, he invites brother and sister Peterchen and Annaliese to join him on a journey to the moon in a quest to retrieve his lost arm.
Detective Heinz Ebeling's (Peter Eschberg) car breaks down with a broken windshield and a defective fuel pump on the way to Frankfurt. On the way to the next village, Ebeling witnesses a murder and other crimes, which he tries to solve.