"Kami Histeria" tells the story of five college friends who are part of a band called Kami Histeria.They have just moved into a secluded flat near a jungle in order for them to have their jamming and practice sessions easily. However, since moving into the flat, the five of them are often awakened by screeching in the middle of the night. The band decides to ignore the screeching as sounds of owls from the jungle and continue to record their new single. But after the song goes live on YouTube, their lives are forever changed...

Fahim is an imprudent photographer who does not get along with his colleagues except Nuryn whom he treats as a friend as they share a common passion for their work. One day, Fahim learns that his mother has adopted Fikri, a boy who has been diagnosed with leukemia. Stressed and unhappy, he doesn't seem to understand why his mother insists on taking care of the boy. With Nuryn's help, he manages to find out Fikri's background and the secret that his mother has been hiding all these years.