这部纪录片讲述了一群有抱负的倡导者的故事：他们在海地拯救生命的使命转变成了为医疗保健和正义而战的全球性运动。

Eight Rwandan children leave their families behind to embark on a life-or-death journey seeking high-risk heart surgery in Sudan. Their hearts ravaged by a treatable disease from childhood strep throat, they have only months left to live. Open Heart reveals the intertwined endeavors of Dr. Emmanuel, Rwanda's lone government cardiologist fighting to save the lives of his young patients, and Dr. Gino, the Salam Center's head surgeon, who is fighting to save his hospital, Africa's only link to life-saving free cardiac surgery for the millions who need it.