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Gezeigt wird die Geschichte eines jungen Mannes, Riki-Oh, der mit einer übermenschlichen Kraft gesegnet ist. Nachdem er einen Yakuza-Boss umbringt, da dieser für den Tod seiner Freundin verantwortlich ist, wird Riki-Oh in ein Hochsicherheitsgefängnis gesperrt.
Riki finds himself in the town of Misaki, dotted with illegal nuclear power plants and run by a religious fanatic military organization called "God's Judgment." He is taken prisoner and made to fight in gladiatorial matches in a sprawling arena. He finds his brother, whose special powers have given him the name of "Savior," but his reunion with his resentful sibling turns sour rather quickly.