McCall endeavors to help an escaped prisoner wrongly accused of murder who is too distrustful of the justice system that failed him to accept her aid. Also, McCall worries when her daughter, Delilah, stops hanging out with a close friend, and Detective Dante's search for McCall takes an unexpected turn.

McCall is hired by a concerned mother who suspects her teen son has joined a local gang, leading McCall to the boy’s surprising motivation behind his spiraling behavior. Also, Delilah faces anxiety as she prepares to speak at her friend Jason’s memorial service, and Dante worries when the new detective pursuing McCall sets his sights on unmasking the people closest to her.

McCall and Mel help a deported woman track down her son after she was separated from him while seeking asylum at the U.S. border. Mel, McCall and Bishop exhaust every avenue to get Harry released from prison.

McCall's vigilante work further complicates her personal life when she is forced to ask her ex-husband, Dr. Miles Fulton, to help with a gunshot victim: one of two women being hunted by thieves after they witnessed a robbery.