After receiving a cryptic, urgent distress call from Dr. Beverly Crusher, Admiral Jean-Luc Picard enlists help from generations old and new to embark on one final adventure: a daring mission that will change Starfleet, and his old crew forever.

Aided by Seven of Nine and the crew of the U.S.S. Titan, Picard makes a shocking discovery that will alter his life forever – and puts him on a collision course with the most cunning enemy he’s ever encountered. Meanwhile, Raffi races to track a catastrophic weapon – and collides with a familiar ally.

Picard grapples with an explosive, life-altering revelation, while the Titan and her crew try to outmaneuver a relentless Vadic in a lethal game of nautical cat and mouse. Meanwhile, Raffi and Worf uncover a nefarious plot from a vengeful enemy Starfleet has long since forgotten.

With time running out, Picard, Riker and crew must confront the sins of their past and heal fresh wounds, while the Titan, dead in the water, drifts helplessly toward certain destruction within a mysterious space anomaly.