Tazuna is a young boy who loves to fix things. But his life takes an unexpected turn when he meets a girl who's lying on a hospital bed in an electronically locked lab. When he takes her hand, he finds out that he can never let go, or she will die. On top of that, he has to battle a man and his partner in something called the Ziggurat, and he doesn't have a power of his own. Can he unlock the might of the Hand Shakers?

Tazuna and his new friend Koyori have a problem: If Tazuna lets go of Koyori's hand, she'll die! Can he take her home with him and explain to his parents why he now has to live with a girl? And how's he going to take a bath with her!?