A ruthless defense attorney and no-nonsense law professor at a Philadelphia university selects a group of her best students to work at her firm.

Annalise takes on a new client, Max St. Vincent, an eccentric millionaire who is the key suspect in his wife's brutal murder. All the clues point to St. Vincent as the killer, but Annalise challenges her students to prove he's innocent - whether that's the truth or not. Meanwhile, Annalise deals with issues in her own home when her growing suspicions that Sam is somehow involved in Lila's disappearance start to affect their marriage. In flash forwards, we go back to the night of the murder and learn that Wes might be hiding a few secrets of his own.

Annalise helps Paula Murphy, a suburban soccer mom, get released from jail after she was arrested for a misdemeanor, but just as she’s about to walk free, she’s arrested again by the FBI in connection for felony murder. Annalise and her students are tasked with proving her innocence which will depend on the testimony from another suspect in the case. Meanwhile, the Middleton University president asks Annalise to represent Griffin O’ Reilly, the star quarterback who has also been linked to Lila’s disappearance but she’s unable to make a decision until she knows that Sam wasn’t involved in the case. In flash forwards, more clues are revealed and we discover someone else was also there besides the students during the night of the murder.

Annalise and her students uncover a shocking truth while investigating the case of Marren Trudeau, founder and CEO of a major brokerage firm, who has recently been arrested for insider trading. Meanwhile, Wes discovers a cell phone hidden by Rebecca whose contents reveal an unsettling clue in the Lila Stangard murder case.

Annalise takes on a tough case defending a minor who fatally shoots his police officer father. Meanwhile, Annalise and Sam continue to argue over his relationship with Lila, and Wes and Rebecca begin to question Annalise’s motives. In flash-forwards, we learn more about Laurel’s relationship with Frank and why he was calling her the night of Sam’s death.

A case gets personal for Annalise and the team when their client is a man from the projects who was sentenced to death by Asher’s father several years ago. Meanwhile, Wes is still angry at Annalise for hiding information about Lila’s case, so Annalise must convince him to get back in line. In flash-forwards, we find out exactly where Asher was on the night of the murder.

Annalise and the team are focused on Rebecca’s case, but when the judge enforces a gag order, Rebecca takes things into her own hands. Meanwhile, Michaela is surprised by a pre-nup, sparks fly between Laurel and Frank, and in flash-forwards, we find out more about Wes and Rebecca’s relationship.

The team represents a mother who's on trial for killing her family's nanny while on heavy medication. Meanwhile, a shocking discovery is revealed in Lila's case that could change everything for Rebecca and Bonnie's loyalty to Annalise. In flashbacks, we learn more about Lila and Sam's relationship.

It’s the evening of the bonfire and we finally see what exactly happened on the night of Sam’s death.

It’s the day after Sam’s murder and the students are called in to help Annalise find her missing husband, but just how much does Annalise know? And when a surprise visitor shows up in town, getting away with this murder might not be as easy as the students had hoped.

School is back in session after the holiday break and the entire university is talking about Annalise's missing husband. The Keating Five continue to be questioned by the police and we find out exactly how they've been dealing with the guilt of killing Sam. Sam's sister Hannah shows up and has started her own investigation of what happened to Sam.

A stunning discovery in Sam's murder case leads to changes for Annalise and the students. Meanwhile, Annalise tries to keep things business as usual by taking on a new client who is in the mob, but Hannah continues to pressure her for answers.

Annalise is wracked with guilt and turns to an unlikely source for help. Meanwhile, Bonnie must step up and represent a new client accused of rape.

In flashbacks, we start to piece together what really happened the night of Lila's murder. In present day, Annalise takes on a priest who is accused of murdering another priest. Meanwhile, Connor and Oliver take things to a new level in their relationship, and Wes and Rebecca continue to grow suspicious of each other.

Wes, Connor, Michaela and Laurel may have dug themselves in too deep a hole for Annalise to save them, and the shocking truth about Lila's murder is finally revealed.

Annalise and her students must move on with their lives as though nothing has happened, but the students are still reeling over Rebecca’s disappearance. Only Annalise and Frank know that Rebecca was murdered and the two are determined to find out who killed her. Meanwhile, Annalise decides she wants to take on a new client, a brother and sister who are accused of killing their parents. And an old friend surprises Annalise at home and teaches her a valuable lesson.

Annalise and her team are blindsided when investigators try to pin a new charge on the wealthy siblings she's been hired to represent. Meanwhile, things for Annalise become even more difficult when she's brutally cross-examined on the witness stand during Nate's preliminary hearing.

When Annalise takes on a new client, the team must investigate a very high end sex club to get answers. Meanwhile, Annalise is still representing the siblings accused of killing their parents, but the case takes a turn for the worse when a new motive surfaces, and Wes teams up with an unexpected ally.

When a teenager is found murdered in the woods, Annalise and her team is hired to represent an unlikely suspect named in the case. Meanwhile, Asher comes across a shocking confession, and Wes learns new information about Rebecca’s disappearance.

Asher discovers not everything is what it seems when you work for Annalise. Meanwhile, Frank is presented with a situation that hits close to home, and Wes’ search to find out more about Rebecca’s disappearance culminates into an explosive confrontation.

Annalise takes on a new client, a transgender professor accused of killing her husband. Meanwhile, the Keating 5 are left to handle the Hapstall case and they discover a shocking new suspect.

Annalise and the team are hired to represent a client accused of badgering somebody to the point of suicide. Meanwhile, Eve returns to defend Nate after ADA Sinclair serves him for a possible new murder charge, and Bonnie learns about what happened at Trotter Lake.

Philip makes a threatening move and ADA Sinclair may have figured out a way to take down Annalise. Meanwhile, Catherine and Caleb are forced to make a life changing decision.

ADA Sinclair discovers a break in her favor in the Hapstall case, but her actions result in a deadly outcome as details are revealed about the night Annalise was shot, including the person responsible for pulling the trigger.

A few weeks have passed since Wes shot Annalise. Wes and The Keating 5 deal with the fallout from that night, as Annalise is faced with a complicated road to recovery.

Tensions in the Keating household run high, as each student struggles in their own way trying to return to normalcy. In a flashback, we’ll learn new details about Annalise’s past.

With Philip still out there, Annalise tries to keep the team from panicking and get one step ahead of Philip’s threats. Meanwhile, Wes and Laurel start putting the pieces of Wes’ mothers death together, but some things just aren’t adding up on.

Annalise moves forward with a plan to protect the team from Philip but the risk involved may prove to be too dangerous. Meanwhile, Wes continues to search for new information regarding his mother’s death. In flashback, the Mahoney case takes a drastic turn for Annalise’s client.

The Keating 5 are called into questioning by A.D.A Denver about the night Emily Sinclair was murdered. Meanwhile, Caleb goes missing as the manhunt for Philip intensifies. In flashback, Annalise’s tactics in the Mahoney case leads to a devastating result.

Annalise begins to crack under pressure and wants to leave. Frank has to try and accept the things he has done.