Eric enlists the help of a neighbor to stop Matt from smoking, and makes a vain attempt to help Lucy deal with her flowering womanhood.

Shhh! Don't tell anyone, but: Matt and Mary both have mysterious new friends; Simon and his new charge, Happy, could be in the doghouse; and Lucy keeps mum about the object of a crush.

Mary offers to shield Lucy and her "date" from Eric; Matt gets into a scrape while out with a young woman; and Annie goes to Arizona to bring her parents home.

Annie feels abandoned on the day of her mother's funeral when her father bolts for home, Eric counsels a couple and Matt escorts Renee to the hospital after she goes into labor at the post-funeral luncheon.

Annie is livid when her father brings along his girlfriend on a weeklong visit; Mary and Matt pursue new romantic interests; Lucy wants to find out if blondes really have more fun.

Mary undergoes knee surgery, while Matt learns that Michael Towner was the hit-and-run driver; Wilson reveals the truth about Billy to Eric.

Lucy must choose between her new boyfriend Rod and her former boyfriend Jimmy Moon after he is dumped by his old girlfriend Ashley, and wants Lucy back. While Lucy makes her decision, the rest of the Camden children are making bets to which guy Lucy will choose. Eric and Annie are at odds when they help newly married couples communicate with each other, but end up getting into a big fight themselves when discussing their burial plot arrangements within their own families. Also, a visit from Annie's father stirs up further problems in the Camden household when he arrives without Ginger after recently breaking up due to his hair piece (toupee).

Eric and Annie's parents arrive right in the middle of the crisis involving Mary and Matt; and Happy's original owner comes to take him back.

Annie's father, Charles is getting married to his girlfriend Ginger. The wedding reception is supposed to be at the Camden's house and Annie is the one in charge of preparing the menu. Annie isn't enthusiastic about the wedding and the reception. On her way to the grocery store, she meets a homeless veteran and invites him home. He is the one ending up preparing the menu since he was a chef for forty years. Also, Matt and Mary are taking a little road trip, which ends up being very long when they get a flat tire. Simon is spending the day with his new girlfriend Deena. Lucy is spending the day with Jordan, the guy she can now call her boyfriend. Lastly, Ruthie is feeling lonely, so she pretends her imaginary friend Huey is back the whole day.

When Ginger pays the Camden family a visit, she informs Eric and Annie that her father is in the early stages of Alzheimer's Disease. At first, Annie can't believe it, but after observing him in the backyard and not paying attention to a fire in the barbecue, Annie realizes the truth. Meanwhile, Mary and Eric can't see eye-to-eye on her relationship with Robbie, but they soon agree to compromise. When Mary informs Robbie of the plan, he tells her that it won't work between them. Fortunately for Mary, Robbie changes his mind after talking to Eric in the local grocery market. Also, Lucy gets into trouble after blowing off a Habitat for Humanity project to go on a date, and is caught. Meanwhile, Matt is consumed with depression due to Shana's upcoming move to New York. By this, Matt pays no attention to Simon, who just wants to spend time with his big brother. Also, Ruthie makes a vast millenium preparations until Eric provides her with a more grounded perspective.

Eric and Annie desperately try to figure out how Mary managed to pay her credit card bill while the kids team up to throw them off the scent. When the parents vs. children game finally breaks down, drastic changes happen. After learning that Mary stole from the twins to pay her bills, Eric and Annie come to the heart-breaking realization that they must take drastic action to help their misguided daughter and to protect and preserve the family. The Camden's gather to confront Mary with their feelings of hurt and betrayal and their conclusion to send her away to Buffalo with ""The Colonel"" and Grandma Ruth.

The Glenoak Community is making a big fuss over a petition that is protesting the apparently unfair firing of one of Ruthie's teachers, Mrs. Miller at her private school. Annie's father Charles drops by at the Camden's for a visit. Annie is then surprised and shocked when she she learns she has a half-sister.

Annie's father Charles shows up at the Camden household for a weekend visit as Ginger supposedly needs to get away for a bit. But Eric forgot to tell his wife about it and nearly everyone in the Camden household is too busy to spend time with the elderly man. So Grandpa Charles takes Simon to get his learner's permit for driving and they end up being the center of a televised police-pursuit. Eric lies to Annie about his plans for the day, which include a trip to Glenoak Hospital.

Matt and Sarah grieve over Eric's decision not to attend the nuptials following his argument with Rabbi Glass over Matt's conversion to Judaism. Hoping to patch things up between their fathers, Matt and Sarah seek their mothers' help in persuading them to put aside their differences before it's too late. Ben and Kevin come to Glenoak to meet up with Mary and Lucy so that they can resolve their problems. Robbie tries to figure out why Ruthie wants him to move out of the Camden household.

When a nasty thunderstorm rolls through the region and threatens to postpone Lucy and Kevin's wedding, everyone scrambles to make it to the church in time. Mary barely catches the last flight in and brings Matt with her. Chandler and Roxanne rush to pick up Ben and his mother who are stranded at the airport in Las Vegas, but tensions run high and a fist fight breaks out; and Matt gives Lucy some very special brotherly advice when she confesses to pre-wedding jitters.