Ernesto's ""murder"" puts Miguel in control of the cartel and at odds with a pair of associates opposed to his new role. Meanwhile, Klein turns to a client (Darius McCrary) for help in getting out of the trade; and Delia steps up her plan to avenge her partner's murder. Lupita: Elpidia Carrillo. Manny: Danny Trejo. Tio Beto: Miguel Sandoval. Marlene: Sheryl Lee.

Miguel goes into business with a shady new doc who wants to amp up Cadena's supplies, just as Chato gets into bed with a lady (Maria Conchito Alonso) with dangerous family ties. Meanwhile, Marlene's dirty little secret comes out in time to put half her family in joepardy; and Klein turns to a less-than-reliable source to improve his tragically compromised finances.