Anton Reisner, a reistance leader in a tyrannical country, has been imprisoned in the automated Trast Prison and is being tortured by Major Zelinko in order to get the names of the other resistance leaders. The IMF must get him out of the prison. Reisner is in a video-monitored escape-proof glass cubicle. Barney and Willy get themselves imprisoned when Cinnamon as head of the country's prison system arrives for an inspection. She distracts Zelinko long enough for Barney and Willy to escape, wreck the video system, and get to Reisner. But..they tell him to stay in the cell but act different, then get recaptured. Zelinko notes the discrepancy between the door counter and the written log and puts two and two together (incorrectly) with Reisner's odd behavior and assumes Reisner is an imposter. Zelinko and Gulka plot to keep the switch secret but Cinnamon arranges for Zelinko's underling Vasney to overhear it. She has Zelinko arrested and takes Barney, Willy, and the Reisner-as-the-imposte

Carl Vandaam, a bankrupt European tycoon, is masterminding the theft of plutonium to make a hydrogen bomb and sell to the highest bidder. To keep such a bomb from falling into the wrong hands the IMF must stop Vandaam. Jim and Cinnamon get close to Kura, one of the bidders, by offering to bankroll him in return for oil rights. Vandaam demonstrates the bomb's plutonium core but afterwards Barney manages to steal the plutonium and replace it with an empty cylinder. Vandaam's aide discovers the theft and seals the building while Vanddam bluffs it out hoping they catch the thief before the bidding is over. Kura wins the bidding unaware that Cinnamon has planted a device in his money. Cinnamon insists they see the plutonium again, Vandaam is forced to reveal the theft, and Kura wants a refund. Cinnamon destroys the money by remote control. Kura has Vandaam shot while the IMF escape and summon the authorities.

Dr. Erich Rojak and his wife Anna are being held in an underground laboratory/bunker by a totalitarian enemy government. Another unfriendly government has sent an assassin, Ventlos, to kill Rojak. The IMF must rescue Rojak and his wife, destroy the test missile Rojak is working on, and stop Ventlos. The IMF infiltrate the base and Jim introduces a handstamp system, unaware that Ventlos has already replaced the bunker's security chief. Jim uses his system to expose security officer Cinnamon as a phony and she is imprisoned near Anna. Willy breaks in via the furnace and rescues Anna while Cinnamon takes her place...

With Cinnamon-as-Anna in place, she is taken to her ""husband"" and tells Dr. Rojak to be near an air vent. Jim as a security officer has placed a small remote-control flying disk in the bunker's air vent system and it holds a hypo. Barney steers it to Rojak's monitored cell and he uses the hypo to induce a heart attack. Jim summons Rollin (as a heart specialist) who advises surgery and instructs that ""Anna"" be at her husband's side. Ventlos the assassin plans to disrupt the operation by taking Rollin's place in disguise and the IMF quickly has to readjust when Ventlos tries to kill Rojak and destroy the installation.

The IMF must break up a drug-smuggling ring - Bracken gets his drugs from Mexico compliments of Diego Maximillian, who gets his drugs legally from C.W. Cameron. The IMF must connect Cameron to Bracken. Jim plays a Syndicate man who orders the pills from Bracken, and Barney tracks the shipment and switches out the drugs. The team has Maximillian picked up in Mexico so that Bracken has to go directly to Cameron to buy the drugs - the IMF get everything on camera and turn them both over to the authorities.

In the Middle East Willy and Barney infiltrate a chemical plant to gain access to Dehominant-B, a quick-acting lethal gas. Barney is exposed to Dehominant-A while trying to get to the computer and crippled - Willy escapes and Barney is captured. Barney is interrogated and only has four hours to live. The team find out that Dr. Jerry Carlin, a dropout, is the only other person with the skills to access the computer. When Carlin rejects the team's appeal for help, Jim and Paris frame Carlin's girlfriend and threaten to keep her in jail unless he helps them. Dana provides a distract and Paris takes the head scientist Vazan's place and have Barney first fake a confession implicating the technicians and then his own death - they get Barney to the autopsy room where Doug revives him in the nick of time. Jim and Carlin take the incriminated technicians' place and Carlin manages to ruin the Dehominant and erase the computer, then everyone escapes with Vazan.

Joe Corvin, a Syndicate money handler, ships millions through Swiss banks and the IMF must put him out of business. Corvin uses a courier that the IMF set up - Corvin has him killed and needs a new courier. Casey steps in as his mail-order bride addicted to drugs by airline employee-smuggler Jim. Corvin and Jim become partners but when the IMF fake-tightenes up security, they need a new way. Casey fakes her death and Corvin ships the cash in her coffin. Barney steals the money and the coffin is dropped on the runway, revealing a fake corpse. Corvin is confronted by the Syndicate, and an alive Casey shows up with two tickets to Miami. The Syndicate let Casey go and dispose of Corvin, permanently.