All eyes are on Mackenzie Allen as she hosts her first official summit with the Russian President -- which is threatened to be overshadowed by Nathan Templeton's plan to engineer a series of cabinet resignations to coincide with the summit. Templeton goes after Mac with a vengeance, vowing to run - and win - against her in the next presidential election. Meanwhile, as First Gentleman, Rod must host his first state dinner for the Russian President and his wife.

When a tell-all book is published about Mackenzie Allen that contains confidential information suspicions arise. Meanwhile, the confirmation hearings for Vice Presidential nominee Warren Keaton begin, but raise questions about his past.

While Mac is busy working on her first State of the Union address, Rod becomes a tad tipsy and is found in compromising position with an intern for all the world to see. Meanwhile, Templeton sets out to find a way to sabotage Mac's Homeless Initiative Bill. Plus, Dickie and Jayne, who has gone back to being Templeton's chief-of-staff, go out on a dinner date.

Mac wants her Attorney General to look into an urban situation in Maryland because it's where Gardner is from. Mac is also briefed on the situation of the missing surface-to-air missiles that went down in a military plane crash over Pakistan and has to make sure that the weapons do not end up in the hands of terrorists. Templeton is ralling support for the Templeton Act which focuses on domestic crime and Mac is threatening to use her veto power in the hopes for more law enforcement and education over the bill's calls for tougher sentencing. Dickie learns that Vince is planning a commitment ceremony with his partner and he warns him not to invite Mac because it might hurt her in the polls.

Mac suffers a burst appendix while aboard Air Force One. Since there is no Vice President in place, Templeton becomes acting President since he is the Speaker of the House and next in line. Meanwhile, there is an air strike that is crippling travel on Memorial Day weekend and Templeton ends up overstepping his bounds and handles the situation the way he wants to.

After a critic of the Equal Rights Amendment passes away and his wife takes over his seat, Mac believes she can amend the Constitution and pass the ERA once and for all. Meanwhile Templeton turns a Get Out the Vote campaign meeting into a presidential debate, Rod is asked to write a story about his relationship with Mac, and Rebecca finally learns the identity of her IM buddy, and both are shocked at just who the other person is.