Mom and Dad decide to let Cow have a pet. She choose an anaconda, after it eats Chicken, and she hears his voice from inside the snake, and assumes the snake can sound just like Chicken. Cow names the anaconda, Fluffy, and Fluffy soon grows attached to Chicken, as its full-coarse dinner.

The Red Guy hosts a new late night talk show called ""Dead Ghost, Coast to Coast"", and reminds the viewers that tonight's Halloween. Chicken calls in, and is instructed to dress as a human being. So, Cow and Chicken go trick or treating as Mom and Dad, only to find that the neighbors assume that a grown man and woman are trick or treating. With that, Super Cow and Chicken teach The Red Guy a lesson.

Cow, Chicken, Flem, and Earl try out for the school's sumo wrestling team. For being big and fat, Cow is the new team member. Soon, everyone fears her, and she feels degected, but it benefits Chicken, because now no one will beat him up.

Dad is sick of his high-tech reecliner always malfunctioning, so he decides to dump it. Before he does, Cow and Chicken decide to see what it's like to sit in ""The Chair"". They, and they get stuck, and are taken away to museums, and in stolen vans, and finally back at home, where Dad waits for his ""new chair"".

Mom and Dad are upset that Cow and Chicken aren't afraid of the dark, so they call in a specialist on fear: The Red Guy (who portrays Dr. Lackslacks). He tries everyway he can to make Cow and Chicken afraid, only succeeding in making himself afraid of everything.

Mom and Dad go out of town, leaving Cow as the babysitter, because she's the biggest, and not the oldest. Pretty soon, Chicken is at the mercy of his sister's babysitting technique: eating marshmallow soup for supper, doing homework with Crabs the Warthog doll, Piles the Beaver doll, and Manure the Bear doll, taking a bath and being scrubbed with dishsoap, and wearing diapers.

Cow brings home an ""invisible"" dog, whom she dubs, Kevin. Pretty soon, she and Kevin are inseperable, but causes trouble with school and friends. After she enters Kevin in a dog show, and wins, Kevin ""runs away"". Afterwards, Cow finds Kevin, befriended an ""invisible"" homeless man.

Cow and Chicken are taking a trip all by themselves. Their taking an airplane. Once Chicken sees the actual plain, he starts to have anxiety attacks and believes that flying is a dangerous way to travel.

Cow wonders about the day she was born. Chicken tells her she was adopted, Mom tells her that the stork delivered her, Dad said they found her in a cabbage, Teacher says she hatched from an egg, and Red Guy says he delivered her.

Cow bakes her own pie and wants Chicken to try it...but he doesn't want to. Cow then follows Chicken everywhere until she takes drastic measures...hiding all of the food in the house, only leaving the pie. Chicken gives in, and discovers the pie is actually good. Little does he know...it's really poop.

Dad isn't friendly terms with the new neighbors, who happen to be clowns. Cow falls in love with the clown son, who in return falls in love with Cow. They play hooky to spend the day together. Dad finds out, and Cow in grounded, while he kicks the clown son out, and chews clown dad out.

Chicken's dream is to be a world famous figure skater, so he and Earl enter a figure skating contest. Red Guy is jealous because his partner is Flem, so, he injures Earl, making Chicken helpless out on the rink...until Cow comes to save Chicken's dream.

Dad loves shopping for Mom's stuff. He runs off to get a manicure for her, while Cow and Chicken pay for the other items. The censors go off when Cow passes through, so Red Guy, as a mall cop, chases Cow and Chicken all over the store. Cow learns that the censors have been broken for weeks. Red Guy walks through, and is arrest by the REAL mall cops.

Cow wakes up in the middle of the night and finds a monster in the closet. Mr. Monster is actually quite friendly, and the next day, Cow treats him to a grand day out. They enjoy jumping ropes, eating ice cream, and watching TV. But when Mom and Dad discover this, they freak out, and have Cow banish Mr. Monster in the closet forever.

Red Guys shows up at Cow and Chicken's house, posing as Hives the Butler. For the rest of the day, he tries to make Cow and Chicken's life easier, by answers questions for them, peeing for them, feeding them, blinking for them, and giving them story time. When Red Guy discovers that their not wealthy, he decides to take his scam to Flem and Earl.