Betty Jo and the baby are coming home from the hospital. They'll be staying at the Shady Rest temporarily. Hearing that a doctor is coming from Beverly Hills, Billie Jo and Bobbie Jo are hoping that the doctor is a young, handsome, eligible bachelor. The doctor ends up being Granny, who is not what one would consider a traditional doctor. After losing her glasses, nearsighted Granny mistakes Dog for the baby. Granny prescribes a powerful homemade medicine to transform a dog-like baby into a baby-like baby. Steve gives the medicine to Dog. Granny gets her glasses back and when she is shown the baby, she believes she cured her.

Note: This episode concludes a crossover with The Beverly Hillbillies that began on "Granny Goes to Hooterville".

The Cannonball's arch enemy, Homer Bedloe, has arrived in the valley. All he seems to be doing is riding the train. Sam and Joe learn that Bedloe is watching Wendell's performance to use as an excuse to scrap the Cannonball in favor of a bus service for the valley. That would put the Shady Rest out of business as there is no road that goes by the hotel. Janet comes up with the idea to use kindness in dealing with Bedloe's mean ways. They decide to throw Bedloe a birthday party. A cake sent from Granny to the Elliotts ends up playing a part in Janet's plan. Charles Lane's final appearance as Homer Bedloe ends on a happy note, with him finally giving up his quest to shut down the Cannonball.